Welcome to the patient area of the PROTECT-V trial website. This trial aims to enrol patients at particularly high risk of COVID-19 and its complications, and we are looking for drugs which might prevent the disease.
Immunocompromised patients are particularly vulnerable to COVID19 as they are not able to fight the infection as well as others. Whilst we now have vaccines against COVID19, vaccines do not work for everyone. In particular, those that have an immune system that doesn’t work normally, or that take medicines which suppress the immune system, may not get as good protection from vaccines. This is why it is important we find medications that can protect those where vaccines are less effective.
We are recruiting patients from all over Great Britain who are immunocompromised; including but not limited to those in the following groups:
- Those receiving dialysis treatment
- Those with a primary immunodeficiency
- Those who have an Oncology (cancer), Haemato-Oncology (blood cancer) or Haematology (blood disorder) diagnosis, and have received chemotherapy or have a weakened immune system as a result of your disease or treatment
- Those who have a diagnosis of an autoimmune/inflammatory disease and are currently receiving immunosuppression (Prednisolone ≥20mg daily for at least 4 consecutive weeks is considered a form of immunosuppression in this study)
- Those who have received a solid organ or haematopoietic stem cell transplant
Currently we are recruiting to the Sotrovimab arm of PROTECT-V. This is a medicine currently used for the treatment of SARS-CoV-2 infection. PROTECT-V is assessing its ability to prevent COVID19 disease. You can download the full information sheet here.
The following sites (and lead Investigator) are currently actively recruiting participants to the Sotrovimab arm of PROTECT-V:
Addenbrooke's Hospital, Dr Effrossyni Gkrania-Klotsas
QE Hospital, B'Ham, Dr Ben Sutton
Heartlands Hospital Group, Prof Indranil Dasgupta
Royal Devon & Exeter, Dr Coralie Bingham
Royal Liverpool, Dr Richard Fitzgerald
King's College Hospital, Dr Jonathan Dick
Royal Derby Hopital, Dr Nitin Kolhe
St James Hospital, Leeds, Dr Sunil Daga
James Cook Hospital, Dr John Widdrington (closed to recruitment)
Portsmouth Hospital, Dr Alex Hicks
Peterborough City Hospital, Dr Abigail Hollingdale
Hinchingbrooke Hospital, Dr Cheryl Palmer
Royal Papworth, Dr Jasvir Parmar
West Suffolk Hospital, Dr William Petchey (closed to recruitment)
Royal Brompton Hospital, Prof Philip Molyneaux
Harefield Hospital, Dr Vicky Gerovasili
North Manchester General Hospital, Dr Silke Brix
Lister Hospital, Dr Sarah Fluck
Monklands Hospital, Dr Scott Oliver
Hammersmith Hospital, Dr Stephen McAdoo
Derriford Hospital, Dr Lucy Leeman
Ninewells Hospital, Dr Samira Bell
Royal Free Hospital, Dr Sorena Kiani
Queeens Medical Centre, Dr Hiba Mohamad
Sheffield North General Hospital, Dr Ragada El-Damanawi
Check back on our website to see updated lists of sites that are open or due to open soon.
Welcome to the staff area for the PROTECT trial.
We are still looking for new sites! If you are interested in becoming a new PROTECT-V site, or if you are an existing site that wishes to open the Sotrovimab arm, please download and complete our feasibility form and return it to email@example.com. If you need any further information about the study or would like some help/guidance with completion of the feasibility form, please do not hesitate to contact us via firstname.lastname@example.org or by contacting one of the Chief Investigator directly.